![]() ![]() Changes made to the factors that directly affect signal level, and to those variables primarily contributing noise to the system, have an inverse effect on SNR that is reflected in the displayed value. ![]() During image acquisition with electronic sensors, including CCDs, apparently random fluctuations in signal intensity constitute noise superimposed on the signal, and as the magnitude of noise increases, uncertainty in the measured signal becomes greater. As each variable is changed, the calculated value of signal-to-noise ratio is updated in the left-hand yellow box. Parameters that affect signal-to-noise ratio for a CCD sensor can be varied for the system modeled in the tutorial by using the mouse to reposition any of the sliders located below the display window. The tutorial initializes with the display of a graphical plot of signal-to-noise ratio as a function of integration (exposure) time for a hypothetical CCD system with specifications typical of high-performance cameras used in microscopy imaging applications. ![]()
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